Senior Director, Manufacturing, CMC & Supply Chain Technology
Full Time
full time
31 Dec 1969
Verified by Turrior
Content + Source + Freshness • 18 Dec 2025 • 95% confidence
85 / 100
Offer value
High value from a leading genomic medicine company with a strong focus on digital transformation and operational excellence in biotech.
- Lead digital initiatives in a cutting-edge biopharmaceutical company.
- Significant responsibility for driving operation performance.
- Opportunity for progressive career development.
Pros
- Leadership role with a vital impact on manufacturing and supply chain efficiency.
- Involvement in cutting-edge pharmaceutical technologies.
- Strong potential for career advancement within a reputable company.
Cons
- Substantial experience (15+ years) may deter less experienced candidates.
- High-pressure environment adapting to regulatory challenges.
- Limited geographical flexibility expected.
Who it's for
Senior / Executive • Primarily Onsite
Good fit
- Experienced IT professionals with a background in biotech.
- Strategic thinkers ready to navigate complex systems.
- Leaders seeking impactful roles within innovation-driven environments.
Not recommended for
- Less experienced candidates unfamiliar with biotech processes.
- Individuals not interested in a fast-paced work culture.
- Those averse to working in highly regulated settings.
Motivation fit
Desire to lead digital transformations in healthcare.Interest in compliance and operational excellence.Willingness to engage in cross-functional collaboration.
Key skills
Digital transformation and strategyPharmaceutical manufacturing systemsApplication lifecycle managementTeam leadership and stakeholder engagement
Score: 85/100 AI verified analysis
About the job
Shape and execute the digital vision: Define, deliver, and continuously evolve a pragmatic multi-year digital transformation roadmap for Manufacturing, CMC, and Supply Chain, aligned with TOQ and Alnylam's enterprise strategy. Ensure operational excellence: Own the operations, performance, and compliance of core enterprise platforms (e.g., MES, Electronic Batch Records, Process Analytical Technology, Empower, ERP), ensuring reliable, compliant, and efficient system support across sites. Own the application lifecycle: Drive accountability for the full lifecycle of digital applications - from strategy and design through deployment, sustainment, upgrades, continuous improvement, and retirement. Strengthen compliance foundation: Ensure all systems meet GxP, data integrity, and global regulatory standards, maintaining audit readiness and safeguarding uninterrupted supply of medicines. Serve as strategic partner and expert: Act as the primary technology thought partner and domain expert for Manufacturing, CMC, and Supply Chain leaders, aligning digital capabilities with business and scientific priorities. Build and lead a high-performing team: Inspire, develop, and scale a skilled IT organization that supports both transformation and operations, fostering innovation, accountability, and pragmatic problem-solving. Integrate enterprise capabilities: Collaborate across IT domains (Research, Development, Commercial, Data & AI, Infrastructure, Security) and with external partners to deliver cohesive, enterprise-grade digital solutions. Required: Bachelor's degree in Computer Science, Engineering (e.g., Chemical, Industrial, Biochemical, Bioprocess, Biotechnology, or Pharmaceutical), or a related field; equivalent industry experience considered. 15+ years of progressive IT leadership experience with significant exposure to pharmaceutical or biotech manufacturing, CMC, and supply chain. Proven track record managing operations and application lifecycles in regulated (GxP) environments. Deep expertise in core platforms supporting Manufacturing/CMC/Supply Chain (e.g., MES, EBR, PAT, Empower, and ERP) and integration with adjacent systems (e.g., LIMS, QMS). Strong strategic mindset with a pragmatic approach - balancing long-term vision with reliable delivery of measurable business outcomes. Demonstrated success building and leading cross-functional, global teams. Exceptional stakeholder management and influencing skills across executives, scientists, and operations leaders. Advanced degree in Computer Science, Engineering (e.g., Chemical, Industrial, Biochemical, Bioprocess, Biotechnology, or Pharmaceutical), or related discipline. Experience in biotech or pharmaceutical organizations undergoing scale-up or global expansion. Familiarity with emerging digital technologies (AI/ML, IoT, cloud-based manufacturing platforms).
