The Clasen lab in the Department of Microbiology at UTK is seeking a post-doctoral researcher with expertise in adaptive/cell-mediated immunology.

The lab studies the relationship between the host immune system and the commensal microbes that colonize the intestinal tract. We seek to understand how the host tolerates these organisms and what conditions break tolerance. To address these questions, we employ a combination of techniques in molecular biology and immunology, next generation sequencing, and in vitro and in vivo models.

This position is well-suited for an individual with research experience studying mucosal immunity who has strong communication and organizational skills and enjoys working in a team environment.

For more information, contact Dr. Clasen: sclasen@utk.edu

Salary for this full-time position is commensurate with skills and experience and is eligible for benefits from the University of Tennessee.

This position entails contributing to the daily operations of the lab. Specific responsibilities may include, but are not limited to:

• Ordering and maintaining lab supplies
• Organizing and maintaining lab space and databases
• Supporting new lab members and experimental projects

This position will be expected to perform and troubleshoot experiments and maintain detailed laboratory records. Techniques may include, but are not limited to:

• Mouse organ dissection and preparation of cells and tissues for downstream assays
• Protein analysis (ELISA, western blot, immunoprecipitation)
• Cell analysis (cell sorting/separation, flow cytometry)
• Bacterial culturing (aerobic and anaerobic)
• Molecular biology techniques (cloning, DNA/RNA extraction, PCR)
• Microscopy
• Cell culture (2D and 3D)

This position must be willing to work with animals and will be expected to maintain mouse colonies. Specific responsibilities may include, but are not limited to:

• Serving as the primary health contact for animals
• Maintaining a detailed inventory of mouse colonies and ongoing breeding
• Tagging, weaning, and genotyping mice

Minimum Required Education and Experience:

• Doctoral degree in an immunology-related field

Minimum Required Skills and Abilities:

• Ability to be respectful, collegial, and work well with colleagues from diverse backgrounds
• Understanding of basic laboratory safety procedures
• Excellent written and verbal communication skills
• Willingness to work with animals
• Ability to perform the essential functions of the job as outlined in the duties/responsibilities
• Flow cytometry/FACS experience
• Routine molecular biology/immunology techniques
• Animal handling experience

Preferred Skills and Abilities:

• Knowledge of T cell biology

Additional Information:

To apply, please submit the following documents with the online application, along with emailing Dr. Sara Clasen (sclasen@utk.edu) the requested documents. Email subject line should read “Research Assistant Position.”

• CV
• Contact information for three professional references

Review of applications will begin immediately and continue until the position is filled.

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